Posterior mediastinal enterogenous cyst is a rare entity in neonate.The neonate can present with severe cardio-respiratory compromise in the form of respiratory distress, shock, cardiac failure or arrhythmia soon PREPARE after birth which may require immediate surgical intervention.Antenatal screening can demonstrate the cystic mass in fetus early and can help in quick postnatal management.Multidisciplinary management with aspiration of Special Tags the cysts was life-saving in the present case.